Mickey Kaufman was born in Tel Aviv in 1950, and lived there all his life. Born to Dr. Rudolf Kaufman, a Berlin-born economist, and to Oli (Fordes) Kaufman, a native of Vienna. His mother founded in Vienna in 1935 the 'O.P.' publication bearing the initials of her name. She immigrated to Eretz Israel in 1938, and after her marriage to Kaufman changed her name to 'O.K.'

Since 1974, Mickey has served as the firm's CEO and creative director for 25 years. He also published companies that were unfamiliar in the country at the beginning of their careers, such as Super-Pharm and Burgranch. Mickey created the mythological character of Albert Fruits, who became a cultural hero and a regular in the Israeli living room.

In 1995, on the eve of the first anniversary of the assassination of Yitzhak Rabin, Mickey Kaufman initiated a tribute in honor and memory of the Prime Minister. He produced a special memorial candle, which bears the portrait of Yitzhak Rabin, and asked the public to "light a candle for Yitzhak Rabin."

Between the years 1985–1988

He had a regular column in the "Ha'ir" newspaper that bore his name, in which true and fictional Tel Aviv stories he wrote appeared. Continuing his literary path, he told his stories for 11 years on Avi Etgar's weekly show, 'Etgar LaShabbat', which aired on Net 2 on Saturday afternoons. Many of these stories have been adapted and incorporated into his book 'Emergency Stairs', published in 2014.

He was married to Eli Kaufman, and they have a daughter, Roni, a photographer by profession. Since 1988 he has lived in a relationship with Tamar Harari and they have two sons, Omri and Nir. On March 3, 2021 he passed away after a long battle with Parkinson's disease.